The endocrine system

GCSE Biology revision notes, key terms and practice questions.

The endocrine system

  • The endocrine system is made of glands that secrete hormones directly into the bloodstream.
  • The blood carries the hormone to a target organ, where it produces an effect.
  • Compared with the nervous system, hormonal effects are slower but act for longer.

The main glands

  • The pituitary gland in the brain is a 'master gland': it secretes several hormones that make other glands release hormones.
  • The thyroid gland makes thyroxine; the adrenal glands make adrenaline.
  • The pancreas makes insulin (and glucagon). The ovaries make oestrogen and progesterone; the testes make testosterone.

Adrenaline (Higher)

  • Adrenaline is produced by the adrenal glands in times of fear or stress.
  • It increases heart rate and boosts the delivery of oxygen and glucose to the brain and muscles, preparing the body for 'fight or flight'.

Thyroxine and negative feedback (Higher)

  • Thyroxine from the thyroid gland stimulates the basal metabolic rate. It is important for growth and development.
  • Thyroxine levels are controlled by negative feedback: when the level is too high, the pituitary releases less TSH, so less thyroxine is made; when it is too low, more is made.
  • Negative feedback keeps a level steady by reversing any change.

Key terms

Endocrine system
The system of glands that secrete hormones into the blood.
Hormone
A chemical messenger carried in the blood to a target organ.
Gland
An organ that secretes a hormone or other substance.
Target organ
The organ that a hormone affects.
Pituitary gland
The 'master gland' in the brain that controls other glands.
Adrenaline
A hormone from the adrenal glands that prepares the body for 'fight or flight'.
Thyroxine
A hormone from the thyroid gland that controls the basal metabolic rate.
Negative feedback
A control mechanism that reverses a change to keep a level steady.
Metabolic rate
The speed at which chemical reactions happen in the body.

Practise The endocrine system: 10 questions