The endocrine system
- The endocrine system is made of glands that secrete hormones directly into the bloodstream.
- The blood carries the hormone to a target organ, where it produces an effect.
- Compared with the nervous system, hormonal effects are slower but act for longer.
The main glands
- The pituitary gland in the brain is a 'master gland': it secretes several hormones that make other glands release hormones.
- The thyroid gland makes thyroxine; the adrenal glands make adrenaline.
- The pancreas makes insulin (and glucagon). The ovaries make oestrogen and progesterone; the testes make testosterone.
Adrenaline (Higher)
- Adrenaline is produced by the adrenal glands in times of fear or stress.
- It increases heart rate and boosts the delivery of oxygen and glucose to the brain and muscles, preparing the body for 'fight or flight'.
Thyroxine and negative feedback (Higher)
- Thyroxine from the thyroid gland stimulates the basal metabolic rate. It is important for growth and development.
- Thyroxine levels are controlled by negative feedback: when the level is too high, the pituitary releases less TSH, so less thyroxine is made; when it is too low, more is made.
- Negative feedback keeps a level steady by reversing any change.
Key terms
- Endocrine system
- The system of glands that secrete hormones into the blood.
- Hormone
- A chemical messenger carried in the blood to a target organ.
- Gland
- An organ that secretes a hormone or other substance.
- Target organ
- The organ that a hormone affects.
- Pituitary gland
- The 'master gland' in the brain that controls other glands.
- Adrenaline
- A hormone from the adrenal glands that prepares the body for 'fight or flight'.
- Thyroxine
- A hormone from the thyroid gland that controls the basal metabolic rate.
- Negative feedback
- A control mechanism that reverses a change to keep a level steady.
- Metabolic rate
- The speed at which chemical reactions happen in the body.